Description

1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylMethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone is a sophisticated, multi-functionalized tetraazamacrocycle derivative, designed for advanced coordination chemistry and molecular recognition. Its core value lies in its ability to act as a highly selective and stable chelating agent, particularly for metal ions, making it indispensable for research and development in specialized fields. This compound is primarily needed by researchers and manufacturers in pharmaceutical development, diagnostic imaging, and advanced materials science for creating novel metal-based complexes.

Application

• Pharmaceutical Research: As a precursor or intermediate in the synthesis of novel metal-based therapeutic agents, including anticancer or antimicrobial drugs.
• Diagnostic Imaging: Development of advanced contrast agents for MRI (Magnetic Resonance Imaging) due to its strong metal-chelating properties.
• Radiopharmaceuticals: Chelator for radioisotopes (e.g., Gallium-68, Copper-64) used in Positron Emission Tomography (PET) imaging and targeted radiotherapy.
• Catalysis: Serving as a ligand to create highly active and selective catalysts for organic synthesis and industrial chemical processes.
• Chemical Sensors: Component in the design of fluorescent or colorimetric sensors for the detection of specific metal ions in analytical chemistry.
• Materials Science: Building block for functionalized polymers and supramolecular assemblies with tailored properties for electronics or separation technologies.

Basic Information

Item	Details
Product Name	1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylMethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone
CAS No.	406939-93-3
Molecular Formula	C41H44F15N8O8
Molecular Weight	1010.82 g/mol
Synonyms	1,4,8,11-Tetraazacyclotetradecane, 1,4,8,11-tetrakis(2,2,2-trifluoroacetyl)-, 1'-[4-[[4,8,11-tris(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-yl]methyl]benzyl] derivative; TF-TETA derivative; Perfluoroacetylated Cyclam derivative; 1,4,8,11-Tetrakis(trifluoroacetyl)-1,4,8,11-tetraazacyclotetradecane benzyl-linked dimer; CF3CO-Tetraaza Macrocycle Chelator
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.