Description

(R)-2,2μ-Diamino-6,6μ-dimethylbiphenyl, (R)-6,6μ-Dimethyl-2,2μ-diaminobiphenyl, (R)-6,6μ-Dimethyl-1,1μ-biphenyl-2,2μ-diamine, (R)-6,6μ-Dimethyl-1,1μ-biphenyl-2,2μ-diyldiamine is a high-value, chiral biphenyl diamine derivative, distinguished by its specific (R)-configuration at the stereogenic axis. This compound serves as a crucial chiral building block and ligand precursor in advanced organic synthesis and catalysis. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and asymmetric catalysts.

Application

• Chiral Ligand Synthesis: A key precursor for the preparation of axially chiral phosphine, diamine, and N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis (e.g., hydrogenation, cross-coupling).
• Pharmaceutical Intermediates: Serves as a sophisticated chiral scaffold in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring high stereochemical purity.
• Agrochemical Development: Employed in the research and production of enantiomerically pure pesticides and herbicides, where the specific stereochemistry can significantly influence biological activity and environmental safety.
• Material Science Research: Used in the development of chiral polymers, liquid crystals, and advanced organic frameworks (MOFs/COFs) with unique optical or electronic properties.
• Asymmetric Catalyst Preparation: Direct incorporation into organocatalysts or metal-complex catalysts for enantioselective transformations in fine chemical manufacturing.
• Analytical Chiral Stationary Phases: Can be utilized to develop or modify chiral stationary phases for High-Performance Liquid Chromatography (HPLC) to separate enantiomers.

Basic Information

Item	Details
Product Name	(R)-2,2μ-Diamino-6,6μ-dimethylbiphenyl
CAS No.	3685-06-1
Molecular Formula	C14H16N2
Molecular Weight	212.29 g/mol
Synonyms	(R)-6,6μ-Dimethyl-2,2μ-diaminobiphenyl; (R)-6,6μ-Dimethyl-1,1μ-biphenyl-2,2μ-diamine; (R)-6,6μ-Dimethyl-1,1μ-biphenyl-2,2μ-diyldiamine; (R)-BINAM derivative; (R)-2,2'-Diamino-6,6'-dimethyl-1,1'-biphenyl; (R)-DMBINAM; (R)-6,6'-Dimethyl-[1,1'-biphenyl]-2,2'-diamine; (R)-Axially Chiral Diamine
EINECS	Contact for details

Quality Control

Our (R)-2,2μ-Diamino-6,6μ-dimethylbiphenyl is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through comprehensive analytical techniques including HPLC, Chiral HPLC, GC, and 1H/13C NMR. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, enantiomeric excess (ee), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. The compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain purity and chiral integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.