Description

Methanesulfonamide, N-[(11bR)-2,6-bis(3,5-dimethylphenyl)-8,9,10,11,12,13,14,15-octahydro-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoro- is a sophisticated organophosphorus compound featuring a chiral, sterically hindered dinaphthodioxaphosphepin core. This high-value specialty chemical serves as a key chiral ligand or catalyst precursor in advanced asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic routes with high stereoselectivity.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal-catalyzed reactions, including hydrogenation, cross-coupling, and C-H functionalization.
• Pharmaceutical Intermediate Synthesis: Enabling the stereocontrolled construction of complex active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Potential use in the synthesis of chiral polymers or as a building block for advanced molecular devices.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic and organometallic chemistry.
• Process Chemistry: Optimization and scale-up of catalytic processes for commercial manufacturing.

Basic Information

Product Name	Methanesulfonamide, N-[(11bR)-2,6-bis(3,5-dimethylphenyl)-8,9,10,11,12,13,14,15-octahydro-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoro-
CAS No.	2757287-65-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(11bR)-4-[(1,1,1-Trifluoromethanesulfonyl)amino]-2,6-bis(3,5-dimethylphenyl)-8,9,10,11,12,13,14,15-octahydro-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-oxide; Trifluoromethanesulfonamide Derivative of Chiral Dioxaphosphepin; Chiral Dinaphthodioxaphosphepin Triflylamide; (R)-BINOL-Derived Phosphorus Ligand Triflamide; N-[(11bR)-2,6-bis(3,5-dimethylphenyl)octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoromethanesulfonamide 4-oxide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) detailing specifications such as enantiomeric excess (ee), assay, and impurity profiles are available upon request. Our quality system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is sensitive to fluoride and strong alkali; ensure segregation from such materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.