Description

1,1,1-Trifluoro-N-((11bS)-4-oxido-2,6-bis(4-(trifluoromethyl)phenyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)methanesulfonamide is a sophisticated, high-purity organophosphorus compound designed for advanced chemical synthesis. This compound is valued for its unique structural framework, which incorporates a chiral dinaphthodioxaphosphepin core and multiple trifluoromethyl groups, making it a critical ligand precursor or catalyst component in asymmetric transformations. It is essential for R&D and process development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with high enantiomeric purity.

Application

• Asymmetric Catalysis: Serves as a key chiral ligand or precursor for transition metal catalysts in enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral targets.
• Agrochemical Synthesis: Employed in the creation of advanced, chiral pesticide and herbicide molecules with improved efficacy and environmental profiles.
• Material Science Research: Investigated as a building block for specialty polymers or functional materials due to its rigid, fluorinated structure.
• Process Chemistry Development: Utilized in scaling up synthetic routes that require highly selective phosphorus-based auxiliaries or catalysts.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and catalysis within university and corporate research laboratories.

Basic Information

Product Name	1,1,1-Trifluoro-N-((11bS)-4-oxido-2,6-bis(4-(trifluoromethyl)phenyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)methanesulfonamide
CAS No.	2757287-57-1
Molecular Formula	C37H27F9NO5PS
Molecular Weight	823.64 g/mol
Synonyms	(11bS)-4-((1,1,1-Trifluoromethanesulfonamido)oxy)-2,6-bis(4-(trifluoromethyl)phenyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-oxide; Trifluoromethanesulfonamide, N-[(11bS)-4-oxido-2,6-bis[4-(trifluoromethyl)phenyl]-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-; Chiral Dinaphthodioxaphosphepin Sulfonamide; Fluorinated Phosphorus Catalyst Ligand; CAS 2757287-57-1
EINECS	Contact for details

Quality Control

Our production of this high-value specialty chemical adheres to stringent cGMP and ISO 9001 quality management principles. Every batch is characterized using advanced analytical techniques including HPLC, NMR (1H, 19F, 31P), and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and batch-to-batch consistency for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is sensitive to light and strong bases; ensure the storage area is well-ventilated and separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.