Description

(9H-fluoren-9-yl)methyl ((6S,9S)-1-amino-9-isopropyl-6-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)carbamoyl)-1,8,11,14,17-pentaoxo-2,7,10,13,16-pentaazaoctadecan-18-yl)carbamate is a sophisticated, high-purity synthetic peptide derivative designed for advanced research and development. This compound is critical for applications requiring precise molecular conjugation and controlled release mechanisms. It is primarily utilized by pharmaceutical researchers and biotech companies in the development of novel therapeutic agents, diagnostic tools, and targeted drug delivery systems.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel peptide-based therapeutics.
• Prodrug Synthesis: Utilized in the design and creation of prodrugs, where the 4-nitrophenoxycarbonyl moiety can act as a cleavable protecting group or trigger for controlled drug activation.
• Bioconjugation & Labeling: Acts as a versatile linker for attaching peptides to other biomolecules, surfaces, or reporter molecules (e.g., fluorophores) in diagnostic assay development.
• Peptide Chemistry & SPPS: Employed in solid-phase peptide synthesis (SPPS) as a specialized building block for introducing specific functional groups or creating complex peptide architectures.
• Targeted Drug Delivery Systems: Incorporated into the design of ligand-drug conjugates for targeted cancer therapies and other precision medicine applications.
• Biochemical Tool Development: Used to create enzyme substrates, inhibitors, or probes for studying protease activity and other biochemical pathways.

Basic Information

Product Name	(9H-fluoren-9-yl)methyl ((6S,9S)-1-amino-9-isopropyl-6-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)carbamoyl)-1,8,11,14,17-pentaoxo-2,7,10,13,16-pentaazaoctadecan-18-yl)carbamate
CAS No.	2647914-16-5
Molecular Formula	C52H58N10O14
Molecular Weight	1023.08 g/mol
Synonyms	Fmoc-protected peptide derivative; Fmoc-Lys(PNP)-OH derivative; 4-Nitrophenyl (4-(((6S,9S)-18-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-1-amino-9-isopropyl-1,8,11,14,17-pentaoxo-2,7,10,13,16-pentaazaoctadecan-6-yl)carbamoyl)benzyl) carbonate; Nα-Fmoc-Nε-[(4-nitrophenoxy)carbonyloxy]methylbenzyloxycarbonyl-L-lysine peptide conjugate; PNP-activated Fmoc-amino acid derivative; Custom peptide building block 2647914-16-5.
EINECS	Contact for details

Quality Control

This high-value synthetic compound is produced under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for research and development. Each lot is characterized using advanced analytical techniques including HPLC, LC-MS, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and analytical data is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.