Description

Palladium, bromo[dicyclohexyl[3-(1,1-dimethylethoxy)-6-methoxy-2′,6′-bis(1-methylethyl)[1,1′-biphenyl]-2-yl-κC1′]phosphine-κP][4-[[2-(trimethylsilyl)ethoxy]carbonyl]phenyl]-, (SP-4-2)- is a sophisticated, air-stable organometallic catalyst featuring a bulky, electron-rich phosphine ligand. This compound matters for enabling highly selective and efficient cross-coupling reactions, which are fundamental to constructing complex organic molecules. It is specifically needed by R&D chemists and process development teams in the pharmaceutical and advanced materials sectors for synthesizing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate Synthesis: A key catalyst for Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions in API development.
• Advanced Material Research: Used in the synthesis of organic semiconductors, OLED materials, and conductive polymers.
• Agrochemical Manufacturing: Facilitates the creation of novel, complex active ingredients with improved efficacy.
• Academic & Industrial R&D: An essential tool for methodological development in synthetic organic chemistry laboratories.
• Scale-up Process Chemistry: Suitable for transitioning from milligram to kilogram-scale synthesis due to its stability and defined reactivity.
• Fine Chemical Production: Enables the synthesis of high-value, structurally complex fragrance and flavor compounds.

Basic Information

Product Name	Palladium, bromo[dicyclohexyl[3-(1,1-dimethylethoxy)-6-methoxy-2′,6′-bis(1-methylethyl)[1,1′-biphenyl]-2-yl-κC1′]phosphine-κP][4-[[2-(trimethylsilyl)ethoxy]carbonyl]phenyl]-, (SP-4-2)-
CAS No.	2489525-81-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bromo(dicyclohexyl(3-(tert-butoxy)-6-methoxy-2',6'-diisopropyl-[1,1'-biphenyl]-2-yl)phosphine)(4-((2-(trimethylsilyl)ethoxy)carbonyl)phenyl)palladium; Buchwald-Hartwig Catalyst G4; Pd-PEPPSI-IPent(CO2Teoc)Br; Palladium(II) bromide complex with a bulky N-heterocyclic carbene (NHC) and phosphine ligand; (SP-4-2)-Bromo[4-[[2-(trimethylsilyl)ethoxy]carbonyl]phenyl][dicyclohexyl[3-(1,1-dimethylethoxy)-6-methoxy-2',6'-bis(1-methylethyl)[1,1'-biphenyl]-2-yl-κC1']phosphine-κP]palladium; PEPPSI-IPent(CO2Teoc) Pd Catalyst; Air-stable Pd cross-coupling catalyst.
EINECS	Contact for details

Quality Control

Our Palladium catalyst is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high catalytic activity. Each lot undergoes comprehensive analysis, including NMR spectroscopy, HPLC purity assessment, and elemental analysis (Pd content), to verify identity and specification compliance. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain long-term stability and prevent decomposition. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Palladium (Pd) Content	Contact for details
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.