Description

Benzenepropanoic acid, α-hydroxy-β-[[(3E)-1-oxo-3-hexen-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclod is a complex, high-purity synthetic intermediate with a defined stereochemistry, crucial for advanced pharmaceutical research and development. This compound matters as a sophisticated building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring intricate molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries working on next-generation drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of complex drug molecules, especially in oncology and anti-infective research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to develop new chemical entities with targeted biological activity.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale, focusing on yield optimization and impurity profile control.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in API manufacturing.
• Bioconjugation & Prodrug Synthesis: Potential use in creating targeted drug delivery systems or synthesizing prodrugs due to its functionalizable groups.
• Academic & Institutional Research: Utilized in universities and research institutes for studies in organic synthesis, catalysis, and chemical biology.

Basic Information

Item	Detail
Product Name	Benzenepropanoic acid, α-hydroxy-β-[[(3E)-1-oxo-3-hexen-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclod
CAS No.	2243233-98-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Diacetoxy-12-benzoyloxy-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-7,11-methano-1H-cyclodeca[3,4]benz[1,2-e]azulene-9-carboxylic acid derivative; Complex Taxane-like Intermediate; Advanced Steroidal Skeleton Intermediate; Multi-functionalized Cyclic Terpenoid Derivative
EINECS	Contact for details

Quality Control

Our Benzenepropanoic acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.