Description

(3S,4S,6S,9S)-13-[2-(1-Hydroperoxy-1-methylethyl)-4-thiazolyl]-4-hydroxy-12-methyl-9-(1-methylethyl)-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic Acid 5-thiazolylmethyl Ester is a sophisticated synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture, featuring multiple stereocenters and a thiazole moiety, makes it a valuable building block for constructing novel bioactive compounds. This high-purity chemical is primarily targeted at research institutions and pharmaceutical companies engaged in the discovery and synthesis of new therapeutic agents, particularly in areas requiring complex peptide-mimetic or heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), especially for complex target molecules.
• Medicinal Chemistry Research: Used as a key scaffold or building block in drug discovery programs for structure-activity relationship (SAR) studies.
• Peptidomimetic Development: Its structure is valuable for creating peptide analogs with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Can be utilized to develop specialized probes for studying biological pathways and enzyme interactions.
• Process Chemistry & Scale-Up: Employed in route development and optimization for the commercial-scale production of candidate drugs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry with custom synthesis.

Basic Information

Product Name	(3S,4S,6S,9S)-13-[2-(1-Hydroperoxy-1-methylethyl)-4-thiazolyl]-4-hydroxy-12-methyl-9-(1-methylethyl)-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic Acid 5-thiazolylmethyl Ester
CAS No.	2034136-66-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(3S,4S,6S,9S)-13-[2-(1-Hydroperoxy-1-methylethyl)-4-thiazolyl]-4-hydroxy-12-methyl-9-(1-methylethyl)-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic Acid 5-thiazolylmethyl Ester; CAS 2034136-66-6; Thiazolylmethyl Ester Derivative; Hydroperoxy-thiazole Peptidomimetic Intermediate; Complex Thiazole-Containing Ester; Pharmaceutical Building Block 2034136-66-6
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure consistency and reliability for critical research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We support development under cGMP guidelines as required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and handled in a moisture-controlled environment. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.