Description

(6-2-[3-(4-Benzyloxy-phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester is a high-purity, deuterated pyrrole derivative designed for advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or reference standard in the development of novel therapeutic agents, particularly where metabolic stability and pharmacokinetic profiling are essential. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of deuterated drug candidates for improved metabolic stability and extended half-life.
• Reference Standard: Used for analytical method development, validation, and quality control in the production of active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and the exploration of novel pharmacophores in drug discovery programs.
• Metabolic Studies: Acts as a stable isotope-labeled internal standard in LC-MS/MS for precise quantification and metabolite identification in bioanalytical assays.
• Process Chemistry: Employed in route scouting and optimization for the scalable synthesis of complex target molecules.

Basic Information

Item	Details
Product Name	(6-2-[3-(4-Benzyloxy-phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
CAS No.	265989-37-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	tert-Butyl (6-{2-[3-({4-[(Benzyloxy)methyl]phenyl}carbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl)acetate (D5); 265989-37-5; Deuterated Pyrrole Ester Intermediate; tert-Butyl 2-(6-(2-(3-((4-(Benzyloxy)phenyl)carbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate (D5); D5-Labeled Pharmaceutical Building Block
EINECS	Contact for details

Quality Control

Our (6-2-[3-(4-Benzyloxy-phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and isotopic enrichment is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Deuterium Enrichment (NMR/MS)	≥ 95 atom % D
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.