Description

Urea-D4 is a stable isotope-labeled analog of urea, where four hydrogen atoms are replaced by deuterium atoms. This compound is essential for advanced analytical and research applications where precise molecular tracking and quantification are required. It is primarily used by researchers and manufacturers in the fields of pharmaceutical development, metabolic studies, and analytical chemistry as an internal standard for mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the accurate quantification of urea in complex biological matrices like blood, urine, and tissue samples.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Serves as a deuterated solvent or a tracer in metabolic pathway analysis and protein structure studies.
• Pharmaceutical Research & Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to trace the fate of drug molecules.
• Clinical Diagnostics: Utilized in the development and calibration of high-precision assays for measuring urea levels, critical for renal function tests.
• Isotope Labeling Studies: Acts as a starting material or intermediate in the synthesis of more complex deuterated compounds for research.
• Quality Control in Biotechnology: Applied in process analytics to ensure consistency and purity in biomanufacturing.

Basic Information

Product Name	Urea-D4
CAS No.	1433-11-0
Molecular Formula	CO(ND2)2
Molecular Weight	64.07 g/mol
Synonyms	Urea-d4; [2H4]Urea; Carbonyldiamide-d4; Deuterated Urea; Urea (D4); Diaminomethanone-d4; Isotopic Urea; Perdeuterourea
EINECS	Contact for details

Quality Control

Our Urea-D4 is produced under strict quality management systems to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR and MS to confirm deuterium incorporation and purity. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and specific tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.