Description

1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-(2-amino-4,5-dihydro-4-oxo-1H-pyrrolo3,2-dpyrimidin-7-yl)tetrahydro-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8R,9aS)- is a high-purity, complex heterocyclic compound designed for advanced research and development. This specialty chemical serves as a critical building block or intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value materials. It is primarily targeted at pharmaceutical R&D teams and fine chemical manufacturers requiring sophisticated, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Advanced Organic Synthesis: Used as a complex scaffold or building block for constructing intricate heterocyclic systems in academic and industrial research.
• Proteolysis Targeting Chimera (PROTAC) Development: Potential application as a component in the linker or warhead design for targeted protein degradation molecules.
• Chemical Biology Research: Employed in the development of molecular probes and tools for studying biological pathways and enzyme functions.
• Material Science Research: Exploration of its use in creating novel organic electronic materials or specialty polymers.

Basic Information

Item	Information
Product Name	1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-(2-amino-4,5-dihydro-4-oxo-1H-pyrrolo3,2-dpyrimidin-7-yl)tetrahydro-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8R,9aS)-
CAS No.	222854-89-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	tert-Butyl (6aR,8R,9aS)-8-(2-amino-4-oxo-4,5-dihydro-1H-pyrrolo[3,2-d]pyrimidin-7-yl)-2,2,4,4-tetraisopropyltetrahydro-1H,3H,5H-[1,3,5,2,4]trioxadisilocino[7,6-b]pyrrole-7(6H)-carboxylate; (6aR,8R,9aS)-tert-Butyl 8-(2-amino-4-oxo-4,5-dihydro-1H-pyrrolo[3,2-d]pyrimidin-7-yl)-2,2,4,4-tetraisopropyltetrahydro-1H,3H,5H-[1,3,5,2,4]trioxadisilocino[7,6-b]pyrrole-7(6H)-carboxylate; CAS 222854-89-9; Advanced Pyrrolopyrimidine Intermediate; Silicon-Containing Heterocyclic Ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, generated using validated analytical methods such as HPLC, NMR, and MS. We are committed to meeting the exacting standards required for GMP-grade pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.