Description

(5aS,13aβ)-11aα-(1,1-Dimethyl-2-propenyl)-6aα-hydroxy-2,3,6,6a,11,11a-hexahydro-1H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-5,13(5aH,13aH)-dione is a complex heterocyclic compound with a fused polycyclic structure, serving as a high-value advanced intermediate in organic synthesis. Its intricate molecular architecture makes it a critical building block for the development of novel pharmacologically active compounds. This product is primarily targeted at pharmaceutical R&D and fine chemical synthesis sectors requiring sophisticated chiral templates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex alkaloids and potential drug candidates targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Serves as a chiral building block or ligand precursor for catalytic asymmetric transformations.
• Academic & Institutional Research: Utilized in studies exploring novel heterocyclic chemistry, natural product synthesis, and reaction methodology development.
• Fine Chemical Production: Intermediate for manufacturing specialized, high-purity chemicals used in advanced material science.
• Contract Research Organizations (CROs): Supplied to CROs and CDMOs engaged in custom synthesis projects for the biopharma industry.

Basic Information

Item	Details
Product Name	(5aS,13aβ)-11aα-(1,1-Dimethyl-2-propenyl)-6aα-hydroxy-2,3,6,6a,11,11a-hexahydro-1H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-5,13(5aH,13aH)-dione
CAS No.	23454-27-5
Molecular Formula	C22H25N3O3
Molecular Weight	379.45 g/mol
Synonyms	11aα-(1,1-Dimethyl-2-propenyl)-6aα-hydroxy-2,3,6,6a,11,11a-hexahydro-1H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-5,13-dione; (5aS,13aβ)-form; Alkaloid C-22 Intermediate; Pyrrolopyrazinopyrroloindoledione derivative; Fused Indole Alkaloid Scaffold; Chiral Hexahydro Pyrroloindole Dione; Advanced Pharmaceutical Intermediate 23454-27-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity essential for sensitive R&D and synthesis applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and stored in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.