Description

4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-(2,3,4,4,4-pentadeuterio-3-hydroxybutan-2-yl)-1,2,4-triazol-3-one is a sophisticated deuterated triazole derivative, representing a high-value advanced intermediate in modern synthetic chemistry. Its core value lies in its precise molecular architecture, which incorporates deuterium atoms and a complex heterocyclic framework, making it essential for research in metabolic stability and pharmacokinetics. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel agrochemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of deuterated drug candidates, particularly for enhancing metabolic stability and conducting tracer studies.
• Agrochemical Research: Used in the development of next-generation fungicides and pesticides, leveraging its triazole core for targeted biological activity.
• Metabolic Pathway Analysis: Serves as a deuterium-labeled probe in mass spectrometry-based studies to track drug metabolism and distribution.
• Chemical Biology Tool: Employed in the design and synthesis of molecular probes for studying enzyme inhibition and receptor binding.
• Fine Chemical Synthesis: An advanced intermediate for the custom synthesis of complex, high-value specialty chemicals for contract research organizations (CROs).
• Isotope Labeling Standard: Acts as a reference standard in analytical laboratories for quantifying deuterium incorporation in complex molecules.

Basic Information

Product Name	4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-(2,3,4,4,4-pentadeuterio-3-hydroxybutan-2-yl)-1,2,4-triazol-3-one
CAS No.	1217524-77-0
Molecular Formula	C35H35D5Cl2N8O5
Molecular Weight	Contact for details
Synonyms	(2R,4S)-2-(2,4-Dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-4-[[4-[4-[4-[2-[(2,3,4,4,4-2H5)-3-hydroxybutan-2-yl]-5-oxo-1,2,4-triazol-3-yl]phenyl]piperazin-1-yl]phenoxy]methyl]-1,3-dioxolane; Deuterated Triazolone Derivative; 1217524-77-0; Pentadeuterio Triazolone Intermediate; CAS 1217524-77-0; (2R,4S)-Dioxolane Triazolone-d5; 4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2,3,4,4,4-2H5)-3-hydroxybutan-2-yl]-1,2,4-triazol-3-one.
EINECS	Contact for details

Quality Control

Our 4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-(2,3,4,4,4-pentadeuterio-3-hydroxybutan-2-yl)-1,2,4-triazol-3-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and isotopic enrichment analysis, to ensure consistent quality and specification compliance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Deuterium Enrichment	≥ 95 atom % D
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.