Description

10,14-Dioxa-2,6,18,22-tetraazatricosanedioic acid, 12-(13,13-dimethyl-5,11-dioxo-2,12-dioxa-6,10-diazatetradec-1-yl)-7,17-dioxo-12-[[(phenylmethoxy)carbonyl]amino]-, 1,23-bis(1,1-dimethylethyl) ester is a sophisticated, high-purity synthetic intermediate characterized by its complex polyfunctional structure. This compound is of significant value for its role in advanced organic synthesis, particularly in constructing intricate molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and specialty chemical industries for applications in medicinal chemistry and novel material design.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those requiring specific peptide-like or macrocyclic frameworks.
• Medicinal Chemistry Research: Used in the discovery and development of new drug candidates, enabling the exploration of novel chemical space and structure-activity relationships.
• Peptidomimetic Synthesis: Serves as a critical component for creating peptidomimetics—molecules that mimic peptides but with enhanced stability and bioavailability.
• Linker Molecule in Bioconjugation: Its functional groups make it suitable for use as a specialized linker in antibody-drug conjugates (ADCs) or other targeted therapeutic platforms.
• Specialty Polymer & Material Science: Potential monomer or cross-linking agent for developing advanced polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for synthetic chemists in academic institutions and corporate R&D labs conducting cutting-edge organic synthesis.

Basic Information

Item	Details
Product Name	10,14-Dioxa-2,6,18,22-tetraazatricosanedioic acid, 12-(13,13-dimethyl-5,11-dioxo-2,12-dioxa-6,10-diazatetradec-1-yl)-7,17-dioxo-12-[[(phenylmethoxy)carbonyl]amino]-, 1,23-bis(1,1-dimethylethyl) ester
CAS No.	1162069-31-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,23-Di-tert-butyl 12-[(benzyloxycarbonyl)amino]-12-[2-(2-{2-[(2-{2-[(tert-butoxycarbonyl)amino]ethoxy}ethoxy)carbonyl]ethoxy}ethoxy)ethyl] 10,14-dioxa-2,6,18,22-tetraazatricosanedioate; Cbz-PEG4-acid-PEG4-t-butyl ester; Fmoc-PEG4-acid-PEG4-t-butyl ester (related precursor); Heterobifunctional PEG linker, acid and tert-butyl protected; Polyethylene glycol-based branched linker; Z-PEG4-CH2CH2COOH-PEG4-OtBu
EINECS	Contact for details

Quality Control

Our 10,14-Dioxa-2,6,18,22-tetraazatricosanedioic acid ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.