Description

.beta.-D-Allopyranoside, (3aS,4R,5R,6S,6aS)-2-(dimethylamino)-3a,5,6,6a-tetrahydro-5-hydroxy-4-(phenylmethoxy)methyl-4H-cyclopentoxazol-6-yl 2-(acetylamino)-4-O-2-(acetylamino)-2-deoxy-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-.beta.-D-allopyranosyl-2-de is a complex, high-purity glycosylated intermediate with significant synthetic utility. This compound is a critical building block for advanced research and development in medicinal chemistry, particularly for the synthesis of novel carbohydrate-based therapeutics. It is essential for pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation antibiotics, antiviral agents, and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex carbohydrate-based drug candidates, including novel antibiotics and antiviral compounds.
• Glycobiology Research: Used as a substrate or inhibitor in enzymatic studies to investigate glycosylation pathways and carbohydrate-protein interactions.
• Medicinal Chemistry: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Bioconjugation: Employed in the development of targeted drug delivery systems and antibody-drug conjugates (ADCs) due to its functionalizable structure.
• Enzyme Inhibitor Development: Utilized in the design and synthesis of potent inhibitors for glycosidases and glycosyltransferases.
• Chemical Biology Probes: Acts as a core component for creating activity-based probes to study biological processes at the molecular level.

Basic Information

Product Name	.beta.-D-Allopyranoside, (3aS,4R,5R,6S,6aS)-2-(dimethylamino)-3a,5,6,6a-tetrahydro-5-hydroxy-4-(phenylmethoxy)methyl-4H-cyclopentoxazol-6-yl 2-(acetylamino)-4-O-2-(acetylamino)-2-deoxy-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-.beta.-D-allopyranosyl-2-de
CAS No.	186041-08-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-(Acetylamino)-4-O-[2-(acetylamino)-2-deoxy-3-O-benzyl-4,6-O-benzylidene-β-D-allopyranosyl]-2-deoxy-β-D-allopyranoside derivative; Cyclopentoxazole glycoside intermediate; Benzyl-protected allopyranoside intermediate; Complex glycosyl donor; CAS 186041-08-7
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for sensitive pharmaceutical research. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.