Description

Benzamide, N-(1,1-dimethylethyl)-4-[[cis-5'-ethoxy-4-[2-(4-morpholinyl)ethoxy]-2'-oxospiro[cyclohexane-1,3'-[3H]indol]-1'(2'H)-yl]sulfonyl]-3-methoxy-, (2E)-2-butenedioate (1:1) is a high-purity, complex organic compound designed for advanced research and development applications. This material serves as a critical intermediate or reference standard in the synthesis of novel pharmaceutical agents, particularly those targeting specific enzymatic pathways. It is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of proprietary drug candidates, particularly in oncology and neurological disorder research.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing to ensure product purity and consistency.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the efficacy and selectivity of lead compounds.
• Biochemical Assay Development: Serves as a tool compound or inhibitor in high-throughput screening (HTS) campaigns to identify new therapeutic targets.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and pharmacology.
• Process Chemistry: Acts as a starting material or intermediate in the scale-up and optimization of synthetic routes for Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	Benzamide, N-(1,1-dimethylethyl)-4-[[cis-5'-ethoxy-4-[2-(4-morpholinyl)ethoxy]-2'-oxospiro[cyclohexane-1,3'-[3H]indol]-1'(2'H)-yl]sulfonyl]-3-methoxy-, (2E)-2-butenedioate (1:1)
CAS No.	185913-79-5
Molecular Formula	C38H51N3O11S
Molecular Weight	757.90 g/mol
Synonyms	N-tert-Butyl-4-[[cis-5'-ethoxy-4-[2-(4-morpholinyl)ethoxy]-2'-oxospiro[cyclohexane-1,3'-[3H]indol]-1'(2'H)-yl]sulfonyl]-3-methoxybenzamide fumarate (1:1); (2E)-2-Butenedioic acid compound with N-(1,1-dimethylethyl)-4-[[cis-5'-ethoxy-4-[2-(4-morpholinyl)ethoxy]-2'-oxospiro[cyclohexane-1,3'-[3H]indol]-1'(2'H)-yl]sulfonyl]-3-methoxybenzamide (1:1); Spirocyclic benzamide fumarate salt; Pharmaceutical intermediate 185913-79-5.
EINECS	Contact for details

Quality Control

Our Benzamide, N-(1,1-dimethylethyl)-4-[[cis-5'-ethoxy-4-[2-(4-morpholinyl)ethoxy]-2'-oxospiro[cyclohexane-1,3'[3H]indol]-1'(2'H)-yl]sulfonyl]-3-methoxy-, (2E)-2-butenedioate (1:1) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.