Description

.beta.-D-Allopyranose, 2-deoxy-4-O-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-.beta.-D-allopyranosyl-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3,6-bis-O-(phenylmethyl)-, 1-(2,2,2-trichloroethanimidate) is a sophisticated, high-purity glycosyl donor intermediate, specifically designed for complex oligosaccharide synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemical control in the construction of biologically relevant carbohydrate structures. It is primarily utilized in advanced pharmaceutical research, particularly in the development of novel glycoconjugate vaccines, therapeutic antibodies, and other bioactive molecules where specific sugar linkages are essential for function.

Application

• Glycoconjugate Vaccine Development: As a key glycosyl donor for synthesizing complex antigenic oligosaccharide chains.
• Pharmaceutical Intermediate: For the targeted synthesis of active pharmaceutical ingredients (APIs) with carbohydrate moieties.
• Chemical Biology Research: Enabling the study of carbohydrate-protein interactions and glycan function.
• Oligosaccharide & Polysaccharide Synthesis: A building block for automated or solution-phase synthesis of defined carbohydrate sequences.
• Diagnostic Reagent Manufacturing: Used in producing labeled glycans or glycan arrays for diagnostic assays.
• Bioconjugation: Facilitating the site-specific attachment of sugars to proteins, lipids, or other biomolecules.

Basic Information

Item	Details
Product Name	.beta.-D-Allopyranose, 2-deoxy-4-O-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-.beta.-D-allopyranosyl-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3,6-bis-O-(phenylmethyl)-, 1-(2,2,2-trichloroethanimidate)
CAS No.	165874-29-3
Molecular Formula	C58H52Cl3N3O14
Molecular Weight	1097.39 g/mol
Synonyms	2-Deoxy-4-O-[2-deoxy-2-phthalimido-3-O-benzyl-4,6-O-benzylidene-β-D-allopyranosyl]-2-phthalimido-3,6-di-O-benzyl-β-D-allopyranosyl 2,2,2-Trichloroacetimidate; 2-Deoxy-2-phthalimido-β-D-allopyranosyl Trichloroacetimidate Donor (benzyl protected); Glycosyl Donor for Allose Synthesis; Phthalimido-protected Allopyranosyl Trichloroacetimidate; Benzylidene/Benzyl Protected Disaccharide Donor; CAS 165874-29-3
EINECS	Contact for details

Quality Control

Our .beta.-D-Allopyranose derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and Mass Spectrometry. We support compliance with research and development standards, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.