Description

1,5-Anhydro-3-O-[3,4-O-carbonyl-6-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-galactopyranosyl]-2-deoxy-6-O-[(1,1-dimethylethyl)dimethylsilyl]-D-arabino-hex-1-enitol is a sophisticated, protected carbohydrate derivative that serves as a critical advanced synthetic intermediate in organic and medicinal chemistry. Its value lies in its precisely engineered structure, featuring tert-butyldimethylsilyl (TBDMS) protecting groups and a cyclic carbonate moiety, which enables selective reactivity for constructing complex oligosaccharides and glycoconjugates. This compound is essential for researchers and process chemists in the pharmaceutical and biotechnology sectors, particularly for the development of novel therapeutics, vaccines, and diagnostic agents.

Application

• Key Intermediate in Oligosaccharide Synthesis: Used in the stepwise construction of complex carbohydrate chains for glycobiology research.
• Glycoconjugate Drug Development: Serves as a building block for creating antibody-drug conjugates (ADCs), vaccine adjuvants, and targeted therapeutics.
• Medicinal Chemistry Research: Employed in the synthesis of glycomimetics and other bioactive molecules that modulate biological pathways.
• Process Chemistry & Scale-up: Suitable for pilot-scale and commercial-scale synthesis of carbohydrate-based active pharmaceutical ingredients (APIs).
• Biochemical Tool Development: Used to prepare probes and standards for enzyme inhibition studies and diagnostic assays.
• Academic & Institutional Research: A valuable reagent for exploring new glycosylation methodologies and reaction mechanisms.

Basic Information

Product Name	1,5-Anhydro-3-O-[3,4-O-carbonyl-6-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-galactopyranosyl]-2-deoxy-6-O-[(1,1-dimethylethyl)dimethylsilyl]-D-arabino-hex-1-enitol
CAS No.	163228-39-5
Molecular Formula	C28H52O10Si2
Molecular Weight	604.89 g/mol
Synonyms	1,5-Anhydro-3-O-[3,4-O-carbonyl-6-O-(tert-butyldimethylsilyl)-β-D-galactopyranosyl]-2-deoxy-6-O-(tert-butyldimethylsilyl)-D-arabino-hex-1-enitol; TBDMS-protected Galactosyl Donor; 3,4-Carbonate-6,6'-bis-O-TBDMS Galactose Derivative; Protected Hexenitol Galactoside; Carbohydrate Building Block 163228-39-5; Glycosylation Intermediate; 6,6'-Di-O-tert-butyldimethylsilyl-3,4-carbonyl galactosyl donor
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and analyzed under strict quality control protocols to ensure consistency and reliability for sensitive synthetic applications. Our standard pharmaceutical-grade material is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions, preferably in a dry atmosphere or sealed with appropriate desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.