Description

N-[(3S,4R,5S,9R,10R,13S,14R,17R)-4-hydroxy-10,13-dimethyl-17-[(2R)-1-( 3-propan-2-ylidene-4,5-dihydropyrrol-2-yl)propan-2-yl]-2,3,4,5,6,9,11, 12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]acetamide is a high-purity, complex steroidal acetamide derivative of significant interest in advanced pharmaceutical research and development. This compound, identified by CAS No. 159934-15-3, serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents targeting hormone receptors and metabolic pathways. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation endocrine therapies and specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of novel steroidal drugs and hormone analogs.
• Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in pharmaceutical manufacturing.
• Biochemical Research: Employed in in-vitro studies to investigate interactions with steroid hormone receptors and related biological pathways.
• Drug Discovery: Acts as a precursor or a lead compound scaffold for medicinal chemistry programs focused on metabolic and endocrine disorders.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and steroid chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial chemical entities for client-specific research projects.

Basic Information

Item	Detail
Product Name	N-[(3S,4R,5S,9R,10R,13S,14R,17R)-4-hydroxy-10,13-dimethyl-17-[(2R)-1-( 3-propan-2-ylidene-4,5-dihydropyrrol-2-yl)propan-2-yl]-2,3,4,5,6,9,11, 12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]acetamide
CAS No.	159934-15-3
Molecular Formula	C₃₀H₄₅NO₂
Molecular Weight	463.69 g/mol
Synonyms	4-Hydroxy-10,13-dimethyl-17-[(1R)-1-(3-isopropylidene-4,5-dihydro-2H-pyrrol-2-yl)ethyl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetamide; (3β,5α,17β)-17-[(1R)-1-(3-Isopropylidene-4,5-dihydro-2H-pyrrol-2-yl)ethyl]-4-hydroxyandrostan-3-yl acetamide; Steroidal Pyrrolidine Acetamide; 159934-15-3; A steroidal acetamide derivative.
EINECS	Contact for details

Quality Control

Our N-[(3S,4R,5S,9R,10R,13S,14R,17R)-4-hydroxy-10,13-dimethyl-17-[(2R)-1-( 3-propan-2-ylidene-4,5-dihydropyrrol-2-yl)propan-2-yl]-2,3,4,5,6,9,11, 12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]acetamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.