Description

(1S,5R,Z)-5-(tert-butyldiMethylsilyloxy)-3-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-Methylheptan-2-yl)-7a-Methyldihydro-1H-inden-4(2H,5H,6H,7H,7aH)-ylidene)ethylidene)-2-Methylenecyclohexanol is a high-purity, advanced pharmaceutical intermediate characterized by its complex stereochemistry and functional groups. This compound is of critical importance in the synthesis of complex organic molecules, particularly in the development of novel therapeutic agents where precise stereochemical control is paramount. It is primarily sought after by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in steroid analog synthesis and the production of potent bioactive compounds.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of novel steroid-based therapeutics and hormone analogs.
• Research & Development (R&D): Used in academic and industrial R&D for exploring new chemical entities (NCEs) and structure-activity relationships (SAR).
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex target molecules in pilot plants and manufacturing.
• Synthesis of Bioactive Molecules: Integral to the construction of molecules with potential anti-inflammatory, anti-cancer, or hormonal activity.
• Fine Chemical Production: Used by specialty chemical manufacturers to produce custom, high-value intermediates for the life sciences industry.

Basic Information

Item	Details
Product Name	(1S,5R,Z)-5-(tert-butyldiMethylsilyloxy)-3-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-Methylheptan-2-yl)-7a-Methyldihydro-1H-inden-4(2H,5H,6H,7H,7aH)-ylidene)ethylidene)-2-Methylenecyclohexanol
CAS No.	132054-64-9
Molecular Formula	C31H52O3Si
Molecular Weight	500.83 g/mol
Synonyms	5-[(1,1-Dimethylethyl)dimethylsilyl]oxy-3-[(1E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dihydroxy-1,5-dimethylhexyl]octahydro-7a-methyl-1H-inden-4-ylidene]ethylidene]-2-methylene-(1S,5R)-cyclohexanol; TBS-protected steroid synthon; Advanced steroidal intermediate; (1S,5R,Z)-5-((tert-Butyldimethylsilyl)oxy)-3-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-1H-inden-4-ylidene)ethylidene)-2-methylenecyclohexan-1-ol
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure stereochemical purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.