Description

n-Butyldimethylchlorosilane is a versatile organosilicon reagent, specifically a chlorosilane derivative, widely used as a key intermediate and protecting group agent in organic synthesis. Its primary value lies in its ability to introduce the bulky butyldimethylsilyl (BDMS) group, offering enhanced steric protection compared to smaller silyl groups like TMS. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and stable silylation for sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate Synthesis: Used as a protecting group for alcohols, phenols, and carboxylic acids during multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Production: Serves as a key building block in the synthesis of certain pesticides and herbicides where selective protection of functional groups is required.
• Polymer & Material Science: Employed in the surface modification of silica and other inorganic materials, and as a precursor for silicone-based polymers and coatings.
• Organic Synthesis Reagent: A fundamental reagent for introducing the butyldimethylsilyl (BDMS) moiety, providing improved stability for sensitive intermediates in complex organic reactions.
• Analytical Chemistry: Utilized in derivatization techniques for gas chromatography (GC) to enhance the volatility and detectability of polar compounds.
• Specialty Chemical Manufacturing: Acts as a critical intermediate in the production of other functional silanes and silicone specialties.

Basic Information

Product Name	n-Butyldimethylchlorosilane
CAS No.	1000-50-6
Molecular Formula	C6H15ClSi
Molecular Weight	150.72 g/mol
Synonyms	Butyldimethylchlorosilane; n-Butyldimethylsilyl Chloride; Chloro-n-butyldimethylsilane; BDMS-Cl; Dimethylbutylchlorosilane; n-Butyldimethylchlorosilane; 1-(Chlorodimethylsilyl)butane; Butyl(dimethyl)chlorosilane
EINECS	213-677-1

Quality Control

Our n-Butyldimethylchlorosilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this material must be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Density (at 20°C)	0.88 - 0.90 g/mL
Refractive Index (n20D)	1.425 - 1.429
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.