Description

Benzo1,2-b:4,3-bdipyrrole-2-carboxylic acid, 1,2,3,6,7,8-hexahydro-4-hydroxy-8-(hydroxymethyl)-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl-, methyl ester is a complex heterocyclic organic compound that serves as a critical advanced intermediate in pharmaceutical research and development. Its intricate molecular architecture, featuring fused pyrrole and indole ring systems, makes it a valuable building block for synthesizing novel bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of new therapeutic agents, particularly in oncology and neurological disease research.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Oncology Drug Discovery: Building block for potential kinase inhibitors or other targeted cancer therapies.
• Neurological Disorder Research: Intermediate in the synthesis of compounds targeting central nervous system pathways.
• Chemical Biology Probes: Utilized to create tool compounds for studying specific biological processes and protein functions.
• Process Chemistry Development: Serves as a benchmark material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Development (CRO): Supplied to service organizations supporting pharmaceutical innovation pipelines.
• Academic Research: Used in university laboratories for pioneering studies in organic synthesis and drug design methodologies.

Basic Information

Item	Details
Product Name	Benzo1,2-b:4,3-bdipyrrole-2-carboxylic acid, 1,2,3,6,7,8-hexahydro-4-hydroxy-8-(hydroxymethyl)-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl-, methyl ester
CAS No.	125600-37-5
Molecular Formula	C28H28N2O9
Molecular Weight	536.53 g/mol
Synonyms	Methyl 1,2,3,6,7,8-hexahydro-4-hydroxy-8-(hydroxymethyl)-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]benzo[1,2-b:4,3-b']dipyrrole-2-carboxylate; Benzo[1,2-b:4,3-b']dipyrrole-2-carboxylic acid derivative; Hexahydro-4-hydroxy-8-(hydroxymethyl)-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl methyl ester; Advanced Indole-Pyrrole Fused Intermediate; 125600-37-5; CAS 125600-37-5
EINECS	Contact for details

Quality Control

Every batch of this advanced pharmaceutical intermediate is produced and analyzed under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets the exacting standards required for research and development. Our quality protocols are designed to support regulatory filings, with documentation suitable for use under GLP (Good Laboratory Practice) and development toward GMP (Good Manufacturing Practice) standards. Specifications can be aligned with client-specific requirements for critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under controlled conditions to minimize exposure to atmospheric moisture and light. For long-term storage, consider using desiccant packs and storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.