Description

2-Thiophenecarboxylic Acid, 5-(2-Amino-4-Thiazolyl)-, Methyl Ester is a high-purity, heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its unique molecular architecture, featuring fused thiophene and thiazole rings, makes it a valuable building block for constructing complex active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in antibiotic and antiviral development.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides, leveraging its heterocyclic bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the synthesis pathway of final drug substances requiring specific thiazole-thiophene motifs.
• Material Science Precursor: Investigated for use in creating specialized organic electronic materials and ligands for catalysis.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 5-(2-Amino-4-Thiazolyl)-, Methyl Ester
CAS No.	960511-21-1
Molecular Formula	C9H8N2O2S2
Molecular Weight	240.30 g/mol
Synonyms	Methyl 5-(2-Amino-1,3-thiazol-4-yl)thiophene-2-carboxylate; 5-(2-Amino-4-thiazolyl)-2-thiophenecarboxylic Acid Methyl Ester; 2-Thiophenecarboxylic acid, 5-(2-amino-4-thiazolyl)-, methyl ester; 4-Thiazoleacetic acid, 2-amino-α-oxo-, methyl ester, thiophene analog; Thiophene-thiazole carboxylate ester intermediate
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxylic Acid, 5-(2-Amino-4-Thiazolyl)-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and GMP-grade synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.