Description

5-Bromo-1-Methyl-1H-Imidazole is a versatile and high-value halogenated heterocyclic building block essential for advanced organic synthesis. Its core value lies in providing a reactive bromine substituent on a methylated imidazole scaffold, enabling precise molecular construction in complex chemical processes. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral agents, and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the development of modern fungicides, herbicides, and plant growth regulators where the imidazole moiety is a critical pharmacophore.
• Ligand & Catalyst Development: Serves as a building block for N-heterocyclic carbene (NHC) precursors and other specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the creation of organic electronic materials, ionic liquids, and metal-organic frameworks (MOFs) due to its functionalizable structure.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation and the development of chemical probes and enzyme inhibitors.
• Custom Synthesis & Scale-Up: A fundamental starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects.

Basic Information

Product Name	5-Bromo-1-Methyl-1H-Imidazole
CAS No.	1003-21-0
Molecular Formula	C4H5BrN2
Molecular Weight	161.00 g/mol
Synonyms	1-Methyl-5-bromoimidazole; 5-Bromo-1-methylimidazole; 1-Methyl-5-bromo-1H-imidazole; 5-Bromo-N-methylimidazole; 5-Bromo-1-methyl-1H-imidazole; 5-Bromo-1-methylimidazole; 5-Brom-1-methylimidazol (German); 5-ブロモ-1-メチルイミダゾール (Japanese)
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Methyl-1H-Imidazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each production lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial customers, ensuring full traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.