Description

3-Thiophenecarboxylic Acid, 2-[[(2,6-Difluorophenyl)Methyl](Propoxycarbonyl)Amino]-4-[(Dimethylamino)Methyl]-5-(4-Nitrophenyl)-, Ethyl Ester is a high-purity, complex organic intermediate designed for advanced chemical synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its multifunctional structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, or insecticides, leveraging its thiophene and difluorophenyl motifs.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study enzyme function or cellular pathways.
• Material Science Research: Potential monomer or additive for advanced polymeric materials with specific electronic or optical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.
• Academic & Institutional Research: Used in university and government labs for fundamental studies in organic and medicinal chemistry.

Basic Information

Product Name	3-Thiophenecarboxylic Acid, 2-[[(2,6-Difluorophenyl)Methyl](Propoxycarbonyl)Amino]-4-[(Dimethylamino)Methyl]-5-(4-Nitrophenyl)-, Ethyl Ester
CAS No.	2591260-08-9
Molecular Formula	C27H27F2N3O6S
Molecular Weight	559.59 g/mol
Synonyms	Ethyl 2-[[(2,6-difluorophenyl)methyl](propoxycarbonyl)amino]-4-[(dimethylamino)methyl]-5-(4-nitrophenyl)thiophene-3-carboxylate; 2-(((2,6-Difluorobenzyl)(3-ethoxy-3-oxopropanoyl)amino)methyl)-N,N-dimethyl-5-(4-nitrophenyl)thiophene-3-carboxamide (related structure); 2591260-08-9; Advanced Thiophene Ester Intermediate; Difluorophenyl-Thiophene Carboxylate Ester
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment. We support compliance with relevant guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be stored away from light. It may be sensitive to strong bases and should be kept separate from incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to minimize oxidation risk.

Specification

Item	Specification
Appearance	Yellow to light brown solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.