Description

tert-Butyl (3S,4S)-3-Methoxy-4-(Methylamino)Pyrrolidine-1-Carboxylate is a high-purity chiral pyrrolidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its defined stereochemistry and protected amine functionality, which are essential for constructing complex molecules with high enantiomeric purity. This compound is primarily needed by pharmaceutical R&D and process chemistry teams for the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates, especially for central nervous system (CNS) and antiviral targets.
• Asymmetric Synthesis: Utilized as a precursor or ligand in catalytic asymmetric reactions to induce chirality in target molecules.
• Peptidomimetic Research: Serves as a constrained proline analogue for designing and synthesizing peptide-like molecules with enhanced metabolic stability.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical space.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing under GMP guidelines.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting research in synthetic methodology and new reaction development.

Basic Information

Product Name	tert-Butyl (3S,4S)-3-Methoxy-4-(Methylamino)Pyrrolidine-1-Carboxylate
CAS No.	960316-16-9
Molecular Formula	C11H22N2O3
Molecular Weight	230.31 g/mol
Synonyms	1-tert-Butyl 2-[(3S,4S)-3-Methoxy-4-(methylamino)pyrrolidine]carboxylate; (3S,4S)-1-(tert-Butoxycarbonyl)-3-methoxy-4-(methylamino)pyrrolidine; Boc-(3S,4S)-3-Methoxy-4-(Methylamino)pyrrolidine; tert-Butyl (3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinecarboxylate; (3S,4S)-N-Boc-3-Methoxy-4-(Methylamino)pyrrolidine; (S,S)-tert-Butyl 3-methoxy-4-(methylamino)pyrrolidine-1-carboxylate; 960316-16-9
EINECS	Contact for details

Quality Control

Our tert-Butyl (3S,4S)-3-Methoxy-4-(Methylamino)Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled with care in environments free from strong acids and organic solvents to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.