Description

2-tert-Butyl 7-Methyl 3,4-Dihydroisoquinoline-2,7(1H)-Dicarboxylate is a high-purity, protected dihydroisoquinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile and reactive scaffold for constructing complex nitrogen-containing heterocycles, which are pivotal in pharmaceutical discovery and material science. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require a functionalized isoquinoline core.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex molecules used in catalysis, ligands, and specialty materials.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new chemical reactions involving protected amines and esters.
• Chemical Biology Probes: Useful for constructing molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	2-tert-Butyl 7-Methyl 3,4-Dihydroisoquinoline-2,7(1H)-Dicarboxylate
CAS No.	960305-54-8
Molecular Formula	C17H23NO4
Molecular Weight	305.37 g/mol
Synonyms	2-(tert-Butyl) 7-methyl 1,2,3,4-tetrahydroisoquinoline-2,7-dicarboxylate; 1,2,3,4-Tetrahydroisoquinoline-2,7-dicarboxylic acid 2-tert-butyl ester 7-methyl ester; 2-tert-Butoxycarbonyl-7-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline; 2-Boc-7-COOMe-THIQ; 2-(tert-Butoxycarbonyl)-7-(methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline; 960305-54-8; Protected THIQ derivative
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl 7-Methyl 3,4-Dihydroisoquinoline-2,7(1H)-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.