Description

3,4-Dihydro-1H-Isoquinoline-2-Carboxamidine Hydrochloride is a high-purity organic salt compound that serves as a critical building block in advanced pharmaceutical synthesis and chemical research. Its value lies in its role as a versatile intermediate for constructing complex nitrogen-containing heterocycles, which are core structures in many active pharmaceutical ingredients. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or optimize synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of biologically active isoquinoline derivatives and other fused heterocyclic compounds with potential therapeutic applications.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in drug discovery programs targeting various disease pathways.
• Agrochemical Synthesis: Employed in the development of novel pesticides and herbicides that utilize the isoquinoline pharmacophore.
• Chemical Biology Probes: Serves as a starting material for creating specialized probes and inhibitors used to study enzyme function and biological mechanisms.
• Fine Chemical Manufacturing: Utilized in custom synthesis and contract manufacturing for producing high-value, specialty chemicals.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and research institutes.

Basic Information

Item	Details
Product Name	3,4-Dihydro-1H-Isoquinoline-2-Carboxamidine Hydrochloride
CAS No.	1131-66-4
Molecular Formula	C10H12N3·HCl
Molecular Weight	209.68 g/mol
Synonyms	1,2,3,4-Tetrahydroisoquinoline-2-carboxamidine Hydrochloride; 2-Carbamimidoyl-1,2,3,4-tetrahydroisoquinoline Hydrochloride; 3,4-Dihydro-1H-isoquinoline-2-carboximidamide Hydrochloride; Isoquinoline-2-carboxamidine, 3,4-dihydro-, hydrochloride; 2-Carbamimidoyl-3,4-dihydro-1H-isoquinoline Hydrochloride; 1131-66-4; 3,4-Dihydroisoquinoline-2-carboxamidine HCl
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-1H-Isoquinoline-2-Carboxamidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.