Description

1-Isoquinolinecarbonitrile is a versatile heterocyclic building block with significant utility in advanced organic synthesis. Its core value lies in its reactive nitrile group fused to an isoquinoline scaffold, enabling the construction of complex nitrogen-containing molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, serving as a key precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various bioactive molecules, including potential kinase inhibitors, antimicrobial agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the isoquinoline structure for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, luminescent materials, and conductive polymers due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes to study biological processes.
• Dye and Pigment Intermediate: Acts as a key component in the synthesis of specialized dyes and pigments for high-performance applications.

Basic Information

Product Name	1-Isoquinolinecarbonitrile
CAS No.	1198-30-7
Molecular Formula	C10H6N2
Molecular Weight	154.17 g/mol
Synonyms	Isoquinoline-1-carbonitrile; 1-Cyanoisoquinoline; 1-Isoquinolyl cyanide; α-Cyanoisoquinoline; NSC 51128; 1-CNI; Isoquinolinecarbonitrile
EINECS	214-840-9

Quality Control

Our 1-Isoquinolinecarbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.