Description

1-Bromoisoquinoline is a versatile brominated heterocyclic building block essential for advanced organic synthesis. Its core value lies in enabling the construction of complex molecular architectures through efficient cross-coupling and functionalization reactions. This high-purity intermediate is critically needed by research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and material science industries to develop new active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, including kinase inhibitors and other biologically active nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the isoquinoline scaffold for bioactivity.
• Ligand & Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis, such as palladium-catalyzed cross-couplings (Suzuki, Heck, Buchwald-Hartwig).
• Material Science Research: Employed in the synthesis of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs) due to its rigid, planar structure and bromine handle for polymerization.
• Chemical Biology Probes: Utilized to create tagged or modified molecular probes for studying biological processes and enzyme functions.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	1-Bromoisoquinoline
CAS No.	1532-71-4
Molecular Formula	C9H6BrN
Molecular Weight	208.06 g/mol
Synonyms	Isoquinoline, 1-bromo-; 1-Bromo-isoquinoline; α-Bromoisoquinoline; 1-Bromoisoquinolin; 1-Isoquinolinyl bromide; NSC 403697; 1532-71-4; Bromoisoquinoline
EINECS	Contact for details

Quality Control

Our 1-Bromoisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.