Description

Imidazo[1,2-A]Pyridine, 8-(Chloromethyl)-, (As Hcl Salt) is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, featuring both the imidazopyridine scaffold and a reactive chloromethyl group, making it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly for targeting central nervous system (CNS) disorders, infectious diseases, and inflammation.
• Agrochemical Synthesis: Used in the creation of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and enzyme functions due to its modifiable structure.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine, 8-(Chloromethyl)-, (As Hcl Salt)
CAS No.	960235-89-6
Molecular Formula	C8H8Cl2N2 • HCl
Molecular Weight	235.53 g/mol (Free base: 183.04 g/mol)
Synonyms	8-(Chloromethyl)imidazo[1,2-a]pyridine hydrochloride; 8-(Chloromethyl)-1H-imidazo[1,2-a]pyridine hydrochloride; Imidazo[1,2-a]pyridine, 8-(chloromethyl)-, hydrochloride (1:1); 960235-89-6; 8-(Chloromethyl)imidazo[1,2-a]pyridinium chloride
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-A]Pyridine, 8-(Chloromethyl)-, (As Hcl Salt) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.