Description

2,2-Difluoro-2-(Isoquinolin-5-Yl)Ethanamine is a high-value, fluorinated isoquinoline derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring a difluoroethylamine moiety attached to an isoquinoline core, makes it an essential intermediate for the development of novel pharmaceuticals and advanced materials. This compound is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of potential drug candidates targeting neurological disorders and oncology.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-cancer therapeutics.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated scaffold, which can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides, where the fluorine atoms can improve efficacy and environmental profile.
• Material Science: Potential building block for creating specialty polymers, liquid crystals, or organic electronic materials with unique properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and diagnostic agents for biological imaging and target identification.

Basic Information

Product Name	2,2-Difluoro-2-(Isoquinolin-5-Yl)Ethanamine
CAS No.	960119-20-4
Molecular Formula	C₁₁H₁₀F₂N₂
Molecular Weight	208.21 g/mol
Synonyms	5-(2,2-Difluoro-2-aminoethyl)isoquinoline; 2,2-Difluoro-2-(5-isoquinolinyl)ethanamine; 2-Amino-1,1-difluoro-1-(isoquinolin-5-yl)ethane; 5-(2-Amino-1,1-difluoroethyl)isoquinoline; 960119-20-4; Ethanamine, 2,2-difluoro-2-(5-isoquinolinyl)-
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluoro-2-(Isoquinolin-5-Yl)Ethanamine is manufactured and tested under strict quality management systems to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.