Description

4-Chloro-5-Iodo-Nicotinonitrile is a halogenated pyridine derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both chloro and iodo substituents on the nicotinonitrile core, makes it a critical building block for constructing complex heterocyclic systems. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted kinase inhibitors and other small molecule drug candidates.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the creation of organic electronic materials and liquid crystals due to its rigid, halogenated structure.
• Chemical Synthesis: Serves as a versatile substrate for cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution, enabling rapid diversification of molecular libraries.
• Academic & Contract Research: Essential reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	4-Chloro-5-Iodo-Nicotinonitrile
CAS No.	959972-34-0
Molecular Formula	C6H2ClIN2
Molecular Weight	264.45 g/mol
Synonyms	4-Chloro-5-iodopyridine-3-carbonitrile; 3-Cyano-4-chloro-5-iodopyridine; 5-Iodo-4-chloronicotinonitrile; Nicotinonitrile, 4-chloro-5-iodo-; 4-Chloro-5-iodo-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-5-Iodo-Nicotinonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development processes. Certificates of Analysis (COA) detailing specifications such as purity (by HPLC), identity (by IR and NMR), and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.