Description

(1R)-7-Fluoroindanylamine is a chiral amine building block of significant importance in modern pharmaceutical research and development. Its core value lies in its unique fluorinated indane structure, which serves as a critical intermediate for synthesizing novel, biologically active compounds. This high-purity intermediate is essential for medicinal chemists and process development scientists working in the pharmaceutical and agrochemical industries, particularly for projects involving central nervous system (CNS) targets and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, especially in neurological and psychiatric disorder research.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and receptor interactions within biological systems.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	(1R)-7-Fluoroindanylamine
CAS No.	959908-09-9
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	(1R)-7-Fluoro-2,3-dihydro-1H-inden-1-amine; (1R)-7-Fluoroindan-1-amine; (R)-7-Fluoroindanylamine; (1R)-1-Amino-7-fluoroindane; 7-Fluoro-(1R)-indanylamine; (R)-1-Amino-7-fluoro-2,3-dihydro-1H-indene; (1R)-7-Fluoro-1-indanamine
EINECS	Contact for details

Quality Control

Our (1R)-7-Fluoroindanylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and chemical purity, verified by advanced techniques such as HPLC, GC, and NMR. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.