Description

2'-o-Acetyl-5'-o-Benzoyl-3'-Deoxy-3'-C-α-Methyluridine is a sophisticated, high-purity nucleoside derivative designed for advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate, enabling the creation of novel modified oligonucleotides and therapeutic agents. It is essential for researchers and manufacturers in the fields of antiviral drug discovery, antisense oligonucleotide synthesis, and medicinal chemistry who require reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside analog drugs targeting viral infections.
• Antisense Oligonucleotide (ASO) Research: Used in the development of modified oligonucleotides for therapeutic applications in genetic disorders.
• Medicinal Chemistry & Drug Discovery: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Bioconjugation & Probe Development: Facilitates the creation of labeled nucleosides for diagnostic and research probes.
• Academic & Institutional Research: Employed in biochemical studies investigating nucleic acid structure, function, and metabolism.

Basic Information

Product Name	2'-o-Acetyl-5'-o-Benzoyl-3'-Deoxy-3'-C-α-Methyluridine
CAS No.	959843-61-9
Molecular Formula	C20H22N2O8
Molecular Weight	418.40 g/mol
Synonyms	3'-C-α-Methyl-2'-O-acetyl-5'-O-benzoyluridine; 3'-Deoxy-3'-C-methyl-2'-O-acetyl-5'-O-benzoyluridine; 2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-3'-C-methyluridine; 3'-C-Methyl-2',5'-di-O-acyluridine derivative; ABz-3'-C-Me-uridine; 959843-61-9; Modified Uridine Intermediate
EINECS	Contact for details

Quality Control

Our 2'-o-Acetyl-5'-o-Benzoyl-3'-Deoxy-3'-C-α-Methyluridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.