Description

4-Iodo-3-Methylbenzenemethanol is a versatile iodinated benzyl alcohol derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an iodine substituent and a hydroxymethyl group on the methylbenzene ring, makes it a valuable building block for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry research for creating libraries of bioactive compounds.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the iodine atom can be leveraged for further functionalization.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers and advanced organic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings.
• Ligand and Catalyst Development: Utilized to synthesize novel chiral or functionalized ligands for asymmetric catalysis and metal complex formation.
• Chemical Biology Probes: Acts as a starting material for creating tagged molecules or probes used in biochemical and cellular studies.

Basic Information

Product Name	4-Iodo-3-Methylbenzenemethanol
CAS No.	959632-18-9
Molecular Formula	C8H9IO
Molecular Weight	248.06 g/mol
Synonyms	(4-Iodo-3-methylphenyl)methanol; 3-Methyl-4-iodobenzyl alcohol; 1-Iodo-2-(hydroxymethyl)-4-methylbenzene; 4-Iodo-m-tolylmethanol; 959632-18-9; Benzenemethanol, 4-iodo-3-methyl-; AI3-52311
EINECS	Contact for details

Quality Control

Our 4-Iodo-3-Methylbenzenemethanol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our customers' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.