Description

(S)-(+)-3-Methyl-2-Butanol CAS NO 1517-66-4 is a high-purity, chiral secondary alcohol characterized by its specific optical rotation. This compound is a valuable chiral building block and intermediate in the synthesis of complex molecules, offering precise stereochemical control. It is primarily utilized by the pharmaceutical, agrochemical, and fine chemical industries for research, development, and production processes.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material for the production of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Manufacturing: Used in the synthesis of chiral pesticides, herbicides, and fungicides where the biological activity is stereospecific.
• Fine Chemical and Flavor & Fragrance Production: Serves as a precursor for chiral esters and other compounds used in high-value flavors, fragrances, and specialty chemicals.
• Asymmetric Catalysis and Ligand Synthesis: Employed in the preparation of chiral ligands and auxiliaries for catalytic asymmetric reactions.
• Academic and Industrial R&D: A critical reagent in organic chemistry research for developing new synthetic methodologies and exploring structure-activity relationships.
• Electronic Chemicals: Potential use as a high-purity solvent or intermediate in the electronics industry for advanced material synthesis.

Basic Information

Product Name	(S)-(+)-3-Methyl-2-Butanol
CAS No.	1517-66-4
Molecular Formula	C5H12O
Molecular Weight	88.15 g/mol
Synonyms	(S)-3-Methylbutan-2-ol; (S)-(+)-3-Methyl-2-butanol; (S)-3-Methyl-2-butanol; (S)-sec-Isoamyl alcohol; L-3-Methyl-2-butanol; (2S)-3-Methylbutan-2-ol; (+)-3-Methyl-2-butanol; (S)-1,2-Dimethylpropanol
EINECS	216-168-1

Quality Control

Our (S)-(+)-3-Methyl-2-Butanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, optical rotation, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain purity. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Optical Rotation [α]D20	+4.5° to +5.5° (neat)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.