Description

(S)-(+)-3-Hydroxytetrahydrofuran is a high-value chiral building block and versatile intermediate in organic synthesis. Its significance lies in its stereochemically defined hydroxyl group, which is crucial for constructing complex molecules with specific three-dimensional configurations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of antiviral drugs, antibiotics, and other bioactive molecules requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where the biological activity is enantiomer-dependent.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing reaction selectivity and yield.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require enantiopure components.
• Polymer Modification: Acts as a monomer or modifying agent for creating functionalized polymers with tailored properties.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	(S)-(+)-3-Hydroxytetrahydrofuran
CAS No.	86087-23-2
Molecular Formula	C4H8O2
Molecular Weight	88.11 g/mol
Synonyms	(S)-3-Hydroxytetrahydrofuran; (S)-(+)-Tetrahydro-3-furanol; (3S)-Oxolan-3-ol; (S)-3-Hydroxyoxolane; (S)-Tetrahydro-3-furyl alcohol; (S)-3-THF-ol; (S)-3-Hydroxytetrahydrofuran; (S)-3-Hydroxy-tetrahydrofuran
EINECS	Contact for details

Quality Control

Our (S)-(+)-3-Hydroxytetrahydrofuran is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.