Description

(1R,4Aα,8Aα)-Decahydro-1α,4α-Naphthalenediol is a high-purity, stereochemically defined diol derivative of decahydronaphthalene. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, prized for its rigid, fused-ring structure that imparts specific stereochemical and conformational properties to target molecules. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in steroid mimetics and other bioactive molecules requiring a rigid, fused-ring core.
• Agrochemical Research: Used in the development of new pesticides and herbicides where its specific stereochemistry can influence biological activity and selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in enantioselective catalytic reactions.
• Advanced Material Synthesis: Employed in the creation of specialty polymers and liquid crystals, where its diol functionality and rigid structure can modify material properties.
• Fine Chemical Production: Acts as a versatile intermediate for producing other high-value, stereochemically pure compounds for various industrial applications.

Basic Information

Product Name	(1R,4Aα,8Aα)-Decahydro-1α,4α-Naphthalenediol
CAS No.	1127-51-1
Molecular Formula	C₁₀H₁₈O₂
Molecular Weight	170.25 g/mol
Synonyms	cis-Decalin-1,4-diol; (1R,4S,4aS,8aR)-Decahydro-1,4-naphthalenediol; 1,4-Dihydroxydecahydronaphthalene; 1,4-Decalindiol; 1,4-Dihydroxyperhydronaphthalene; (1R,4S,4aR,8aS)-Decahydro-1,4-naphthalenediol; NSC 403697
EINECS	214-423-3

Quality Control

Our (1R,4Aα,8Aα)-Decahydro-1α,4α-Naphthalenediol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.