Description

2-Bromo-4'-Methylacetophenone-D3 is a deuterated isotopologue of a key aryl ketone intermediate, where three hydrogen atoms are replaced with deuterium. This deuteration provides a stable isotopic label, making it an invaluable tool for analytical and synthetic chemistry research. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical sectors for use in metabolic studies, tracer analysis, and the development of novel deuterated active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research: As a stable isotope-labeled intermediate for synthesizing deuterated drug candidates to study pharmacokinetics, metabolism, and bioavailability.
• Analytical Chemistry: Serving as an internal standard in mass spectrometry (MS) and nuclear magnetic resonance (NMR) for the precise quantification of its non-deuterated counterpart in complex matrices.
• Agrochemical Development: Used in the synthesis of labeled pesticides or herbicides to investigate environmental fate, degradation pathways, and residue analysis.
• Material Science: Potential precursor for specialty polymers or organic electronic materials where isotopic purity can influence physical properties.
• Chemical Synthesis: A versatile building block for introducing a deuterated bromoacetyl moiety into more complex molecular architectures.

Basic Information

Product Name	2-Bromo-4'-Methylacetophenone-D3
CAS No.	959605-55-1
Molecular Formula	C9H6D3BrO
Molecular Weight	216.09 g/mol (approx.)
Synonyms	1-(4-Methylphenyl)-2-bromoethanone-D3; 2-Bromo-1-(4-methylphenyl)ethanone-D3; 2-Bromo-4'-methylacetophenone-d3; p-Methylphenacyl bromide-D3; 4'-Methyl-2-bromoacetophenone-D3; 1-(4-Methylphenyl)-2-bromoethanone-1,1,2-d3; Deuterated p-Methylphenacyl Bromide
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced under controlled conditions to ensure high isotopic and chemical purity. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to verify identity, chemical purity, and deuterium enrichment. Certificates of Analysis (COA) detailing these specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.