Description

Ethyl 4-Methyl-2-(2-Oxopyrrolidin-1-Yl)-1,3-Thiazole-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiazole-pyrrolidinone hybrid structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly within the fields of central nervous system (CNS) agents and anti-inflammatory therapies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, especially for neurological and anti-inflammatory applications.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes to construct complex molecular architectures for potential APIs.
• Biochemical Research: Employed as a tool compound to study biological pathways and enzyme interactions related to its pharmacophore.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP-scale production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for pioneering synthetic methodology and heterocyclic chemistry studies.

Basic Information

Product Name	Ethyl 4-Methyl-2-(2-Oxopyrrolidin-1-Yl)-1,3-Thiazole-5-Carboxylate
CAS No.	959307-64-3
Molecular Formula	C11H14N2O3S
Molecular Weight	254.30 g/mol
Synonyms	Ethyl 4-methyl-2-(2-oxo-1-pyrrolidinyl)-1,3-thiazole-5-carboxylate; 1,3-Thiazole-5-carboxylic acid, 4-methyl-2-(2-oxo-1-pyrrolidinyl)-, ethyl ester; 959307-64-3; 4-Methyl-2-(2-oxopyrrolidin-1-yl)-1,3-thiazole-5-carboxylic acid ethyl ester; Ethyl 4-methyl-2-(2-oxopyrrolidin-1-yl)thiazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Methyl-2-(2-Oxopyrrolidin-1-Yl)-1,3-Thiazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.