Description

Cyclobutane, [[dimethyl(1-methylethyl)silyl]oxy]- is a specialized organosilicon compound featuring a cyclobutane ring functionalized with a silyl-protected oxygen group. This unique structure makes it a valuable protected intermediate or building block in advanced organic synthesis, particularly for pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require high-purity, custom synthetic intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and insecticides with specific ring structures.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers and silicon-containing hybrid materials.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing cyclobutane-containing molecules, leveraging the silyl group for selective deprotection.
• Ligand and Catalyst Development: Utilized in the preparation of novel organosilicon ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Cyclobutane, [[dimethyl(1-methylethyl)silyl]oxy]-
CAS No.	959289-85-1
Molecular Formula	C9H20OSi
Molecular Weight	172.34 g/mol
Synonyms	[[(1,1-Dimethylethyl)dimethylsilyl]oxy]cyclobutane; (tert-Butyldimethylsilyloxy)cyclobutane; Cyclobutyloxy-tert-butyldimethylsilane; TBDMS-O-Cyclobutane; Cyclobutyl tert-butyldimethylsilyl ether; O-(tert-Butyldimethylsilyl)cyclobutanol; Cyclobutanol, 1-[(1,1-dimethylethyl)dimethylsilyl] ether
EINECS	Contact for details

Quality Control

Our Cyclobutane, [[dimethyl(1-methylethyl)silyl]oxy]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO 9001 compliance for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Density (at 20°C)	0.85 - 0.90 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.