Description

2-Tosylisoindoline-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific isoindoline core functionalized with tosyl and carboxylic acid groups. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors focused on drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting neurological or oncological pathways.
• API Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Research: Used in academic and industrial R&D for exploring new organic reactions and constructing heterocyclic compound libraries.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of pharmaceuticals.
• Ligand & Catalyst Development: Potential use in the design of novel ligands or organocatalysts due to its distinct molecular architecture.

Basic Information

Product Name	2-Tosylisoindoline-5-Carboxylic Acid
CAS No.	959271-74-0
Molecular Formula	C16H15NO4S
Molecular Weight	317.36 g/mol
Synonyms	5-Carboxy-2-(p-tolylsulfonyl)isoindoline; 2-(4-Methylphenyl)sulfonyl-1,3-dihydroisoindole-5-carboxylic acid; 1,3-Dihydro-2-[(4-methylphenyl)sulfonyl]-5-isoindolecarboxylic acid; 2-(p-Toluenesulfonyl)isoindoline-5-carboxylic acid; 2-Tosyl-1,3-dihydroisoindole-5-carboxylic acid; 959271-74-0; 2-Tosylisoindoline-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Tosylisoindoline-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.