Description

Cyclopentane, [(Butyldimethylsilyl)Oxy]- is a specialized organosilicon compound featuring a cyclopentyl ring protected by a butyldimethylsilyl (TBDMS) ether group. This compound is a valuable silyl-protecting reagent and a key synthetic intermediate in advanced organic synthesis, particularly for the protection of alcohols and phenols. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the multi-step synthesis of complex molecules, where precise control over functional group reactivity is paramount.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for nucleoside and carbohydrate chemistry.
• Protecting Group Reagent: Used to selectively protect hydroxyl groups during complex organic syntheses, offering stability under a wide range of reaction conditions.
• Academic & Industrial Research: Serves as a key reagent in medicinal chemistry and process chemistry research for developing new therapeutic candidates.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, agrochemicals, and advanced materials requiring sophisticated synthetic pathways.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	Cyclopentane, [(Butyldimethylsilyl)Oxy]-
CAS No.	959258-40-3
Molecular Formula	C11H24OSi
Molecular Weight	200.40 g/mol
Synonyms	1-((tert-Butyldimethylsilyl)oxy)cyclopentane; Cyclopentyl tert-butyldimethylsilyl ether; TBDMS-cyclopentyl ether; (Cyclopentyloxy)(tert-butyl)dimethylsilane; tert-Butyldimethyl(cyclopentyloxy)silane; O-(tert-Butyldimethylsilyl)cyclopentanol; Cyclopentanol, 1-[(1,1-dimethylethyl)dimethylsilyl] ether
EINECS	Contact for details

Quality Control

Our Cyclopentane, [(Butyldimethylsilyl)Oxy]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.