Description

1H-Indole-3-Carboxylic Acid,4-(Trifluoromethyl)- is a high-value, fluorinated indole derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both the indole core and a trifluoromethyl group, makes it indispensable for creating novel compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for drug discovery and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, neurology, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Research: Employed in the synthesis of specialized organic materials, including ligands for catalysis and components for organic electronics.
• Biochemical Tool Compound: Serves as a precursor for fluorescent probes or enzyme inhibitors used in biochemical and cellular assay development.
• Academic & Contract Research: Essential for synthetic chemistry research in academic institutions and contract research organizations (CROs) exploring new chemical spaces.

Basic Information

Product Name	1H-Indole-3-Carboxylic Acid,4-(Trifluoromethyl)-
CAS No.	959238-76-7
Molecular Formula	C10H6F3NO2
Molecular Weight	229.16 g/mol
Synonyms	4-(Trifluoromethyl)-1H-indole-3-carboxylic acid; 4-Trifluoromethylindole-3-carboxylic acid; 1H-Indole-3-carboxylic acid, 4-(trifluoromethyl)-; 4-CF3-indole-3-carboxylic acid; 4-Trifluoromethyl-1H-indole-3-carboxylic acid; 959238-76-7; 4-(Trifluoromethyl)indole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-3-Carboxylic Acid,4-(Trifluoromethyl)- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.