Description

2,3-Dihydro-5-(4-Morpholinyl)-1H-Indole is a high-purity organic compound featuring a fused indoline and morpholine structure, serving as a valuable synthetic intermediate. This compound is critical for research and development in advanced pharmaceutical chemistry, enabling the creation of novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for use in medicinal chemistry programs and custom synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its privileged heterocyclic scaffold.
• Agrochemical Development: Intermediate for creating novel active ingredients in crop protection products.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds and probes to study biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.
• Academic Research: Used in university and institutional labs for methodological development and novel heterocycle chemistry.

Basic Information

Product Name	2,3-Dihydro-5-(4-Morpholinyl)-1H-Indole
CAS No.	959238-58-5
Molecular Formula	C12H16N2O
Molecular Weight	204.27 g/mol
Synonyms	5-Morpholinoindoline; 5-(Morpholin-4-yl)-2,3-dihydro-1H-indole; 1H-Indole, 2,3-dihydro-5-(4-morpholinyl)-; 5-(4-Morpholinyl)indoline; 2,3-Dihydro-5-morpholino-1H-indole; 5-Morpholino-2,3-dihydro-1H-indole; 4-(2,3-Dihydro-1H-indol-5-yl)morpholine
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dihydro-5-(4-Morpholinyl)-1H-Indole is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.