Description

4-(Trifluoromethyl)Indolin-2-One is a high-purity, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular scaffold, which incorporates a trifluoromethyl group to modulate the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials requiring fluorinated indoline structures.
• Chemical Biology: Employed as a probe or labeling agent in biochemical studies due to its distinct fluorine signature.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	4-(Trifluoromethyl)Indolin-2-One
CAS No.	959238-47-2
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	4-(Trifluoromethyl)-2-indolinone; 2-Oxo-4-(trifluoromethyl)indoline; 4-Trifluoromethyloxindole; 4-CF3-Indolin-2-one; 959238-47-2; 4-(Trifluoromethyl)-1,3-dihydro-2H-indol-2-one
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Indolin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.