Description

5-(Tetrahydrofuran-2-Yl)Thiophene-2-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, combining tetrahydrofuran and thiophene carboxylic acid moieties, makes it a valuable precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a crucial building block in the design and synthesis of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of advanced organic electronic materials, such as conductive polymers and organic semiconductors, due to its electron-rich thiophene core.
• Ligand and Catalyst Development: The carboxylic acid functionality allows for derivatization into chelating ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	5-(Tetrahydrofuran-2-Yl)Thiophene-2-Carboxylic Acid
CAS No.	959237-71-9
Molecular Formula	C9H10O3S
Molecular Weight	198.24 g/mol
Synonyms	2-Thiophenecarboxylic acid, 5-(tetrahydro-2-furanyl)-; 5-(Oxolan-2-yl)thiophene-2-carboxylic acid; 5-(Tetrahydrofuran-2-yl)thiophene-2-carboxylic acid; 5-(2-Furanyl)thiophene-2-carboxylic acid (related); THF-Thiophene Carboxylic Acid; Furan-Thiophene Hybrid Acid
EINECS	Contact for details

Quality Control

Our production of 5-(Tetrahydrofuran-2-Yl)Thiophene-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.