Description

8-Fluoro-2,4(1H,3H)-Quinazolinedione is a fluorinated heterocyclic compound belonging to the quinazolinedione class, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic incorporation of fluorine, which can significantly alter the biological activity and physicochemical properties of target molecules. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the fluorine atom enhances bioavailability and stability.
• Chemical Biology Probe Synthesis: Employed to create fluorinated probes for studying enzyme mechanisms and protein-ligand interactions.
• Material Science: Serves as a monomer or building block for specialty polymers and advanced organic materials with specific electronic properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and fluorine chemistry.

Basic Information

Product Name	8-Fluoro-2,4(1H,3H)-Quinazolinedione
CAS No.	959236-96-5
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	8-Fluoro-1H,3H-quinazoline-2,4-dione; 8-Fluoro-2,4-dihydroxyquinazoline; 8-Fluoroquinazoline-2,4(1H,3H)-dione; 959236-96-5; 8-Fluoro-2,4(1H,3H)-quinazolinedione; 8-Fluoro-1,2,3,4-tetrahydroquinazoline-2,4-dione
EINECS	Contact for details

Quality Control

Our 8-Fluoro-2,4(1H,3H)-Quinazolinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.