Description

5-(Trifluoromethyl)-1H-Indazole-3-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the indazole scaffold combined with a reactive carboxylic acid group and a metabolically stable trifluoromethyl substituent, making it a versatile intermediate for creating novel molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, particularly in kinase inhibitor and anti-cancer research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the indazole core.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the creation of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and library production.

Basic Information

Product Name	5-(Trifluoromethyl)-1H-Indazole-3-Carboxylic Acid
CAS No.	959236-67-0
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	5-(Trifluoromethyl)-1H-indazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 5-(trifluoromethyl)-; 959236-67-0; 5-Trifluoromethyl-1H-indazole-3-carboxylic acid; 3-Carboxy-5-trifluoromethylindazole; 5-CF3-1H-indazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1H-Indazole-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.